教授、博导，副院长，教育部长江学者特聘教授，中组部青年拔尖人才，江苏省杰青。 曾在哈佛大学-麻省理工人类科技研究中心（Harvard-MIT Human Science & Technology）、哈佛大学-维斯研究中心（Harvard-Wyss Institute）访学。 研究方向：人工智能驱动的蛋白质工程与微生物工程及其在药物递送中的应用。 研究成果发表在 Nat. Biomed. Eng.、Nat. Commun.，PNAS，Sci. Adv.，Adv Mater.等期刊上，并被Science， Nature BME等期刊进行亮点报道和专栏评论。申请发明专利40余项，获得多项国家重点研发计划课题的资助、作为主要完成人获教育部一等奖2项（2/11；2/9），江苏省333工程二层次人才，江苏省“六大人才高峰”高层次人才，江苏省医药科技杰出青年奖等荣誉。
PS： 本实验室为多学科交叉，欢迎具有不同背景的同学加入（计算机、化学、生物、医学、药学）。实验室的目标是在人工智能的辅助下，通过蛋白质工程与微生物工程，实现治疗分子的减毒增效。欢迎对基础研究感兴趣（蛋白质结构与工程、微生物工程）的学生加入，同时也欢迎立志于推动研究成果向临床转化的同学、博士后加入课题组！
长期招收博士后&研究助理。
联系邮箱： [email protected]
实验室英文网站： BioIntelligent Medication
药大学报编委 药学教育编委 药学进展编委 APSB青年编委 《BME&PHS》编委 江苏省生物医学工程学会理事会理事
Zhiyan Li, Xianghui Li, Yanjun Lu, Xudong Zhu, Wenxuan Zheng, Kai Chen, Xingzhou Wang, Tao Wang, Wenxian Guan, Zhi Su*, Song Liu*, Jinhui Wu*，Novel Photo‐STING Agonists Delivered by Erythrocyte Efferocytosis‐Mimicking Pattern to Repolarize Tumor‐Associated Macrophages for Boosting Anticancer Immunotherapy。Advanced materials，2024 Oct 08: 2410937 Xu Haiheng; Xiong Shuqin; Chen Yiyun; Ye Qingsong; Guan Nan; Hu Yiqiao; Wu Jinhui*. Flagella of tumor-targeting bacteria trigger local hemorrhage to reprogram tumor-associated macrophages for improved antitumor therapy. Advanced materials[详情], 2023 Jun 13: e2303357. Zai Wenjing; Yuan Yunong; Kang Lin; Xu Jialong; Hu Yiqiao; Kang Lifeng; Wu Jinhui*. Oxygen penetration through full-thickness skin by oxygen-releasing sutures for skin graft transplantation. Engineering[详情]. 2023 May 29: 10.1016/j.eng.2023.05.006. Yang Liu, Yuchen Wang, Chao Wang, Tiejun Dong, Haiheng Xu, Yunfei Guo, Xiaozhi Zhao*, Yiqiao Hu*, Jinhui Wu*, Hijacking Self-Assembly to Establish Intracellular Functional Nanoparticles. Adv Sci. 2022 Sep 8;e2203027[详情] Huanhuan Chen, Yunfei Guo, Zhewei Zhang, Wenxuan Mao, Chenying Shen, Wei Xiong, Yingfang Yao, Xiaozhi Zhao, Yiqiao Hu, Zhigang Zou, and Jinhui Wu*. Symbiotic Algae–Bacteria Dressing for Producing Hydrogen to Accelerate Diabetic Wound Healing. Nano Letter, 2021, 20 December[详情] Wenjing Zai, Lin Kang, Tiejun Dong, Haoran Wang, Lining Yin, Shaoju Gan, Wenjia Lai, Yibing Ding, Yiqiao Hu, Jinhui Wu*.E. coli Membrane Vesicles as Catalase Carrier for Long Term Tumor Hypoxia Relief to Enhance Radiotherapy. ACS Nano, 2021, 15, 9, 15381–15394.[详情] Wenguang Wang, Haiheng Xu, Qingsong Ye, Feng Tao, Ian Wheeldon, Ahu Yuan, Yiqiao Hu, Jinhui Wu, Systemic immune responses to irradiated tumours via the transport of antigens to the tumour periphery by injected flagellate bacteria. Nature Biomedical Engineering. 2021. [详情]（Highlight in Nature Biomedical Engineering） Chao Wang, Zhaoyi Sun, Chenxuan Zhao, Zhewei Zhang, Haoran Wang, Yang Liu, Yunfei Guo, Bingtao Zhang, Lihong Gu, Yue Yu, Yiqiao Hu, Jinhui Wu*. Maintaining manganese in tumor to activate cGAS-STING pathway evokes a robust abscopal anti-tumor effect. Journal of Controlled Release, 2021, 331,480[详情] Huanhuan Chen， Yuhao Cheng, Jingrun Tian, Peizheng Yang, Xuerao Zhang, Yunhao Chen, Yiqiao Hu*, Jinhui Wu*. Dissolved oxygen from microalgae-gel patch promotes chronic wound healing in diabetes. Science Advance, 2020, 6(20), eaba4311[详情] Zaigang Zhou, Baoli Zhang, Wenjing Zai, Lin Kang, Ahu Yuan, Yiqiao Hu*, Jinhui Wu*, Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy. PNAS, 2019 May 29. pii: 201901987.[详情] Wenguang Wang, Yuhao Cheng, Peng Yu, Haoran Wang, Yue Zhang, Haiheng Xu, Qingsong Ye, Ahu Yuan, Yiqiao Hu, Jinhui Wu*, Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy. Nature communications. 2019, 10:1580.[详情]
更多相关学术工作请访问谷歌学者主页.
国家重点研发计划“纳米科技” 国家重点研发计划“前沿生物技术” 江苏省杰出青年基金 国家青年人才计划 国家自然科学基金面上项目 国家自然科学基金面上项目 国家自然科学基金青年项目
教育部自然科学一等奖 教育部技术发明一等奖 江苏省医药科技杰出青年奖 中国专利优秀奖 江苏省专利金奖
|
